Clinical research on high OPC Pine Bark Extract showed (Shand et al, Young et al):
- Improvements in endothelial function
- Positive changes in inflammatory blood markers, namely plasma viscosity and fibrinogen levels
A 2010 Hallym University (Korea) study further investigated the effects of high OPC Pine Bark Extract on inflammatory processes that initiate atherosclerosis—those that often advance to cardiovascular diseases such as heart attack and stroke. Results showed:
- Modulated monocyte adhesion and transmigration
- Reduced inflammatory events
- High OPC PBE’s potential as a natural therapeutic supplement with anti-inflammatory and anti-atherogenic effects
(Kim, D.S. et al J Agric Food Chem 58: 7088; 2010)